Metabolism
How Your Metabolism Actually Works
Weight is ultimately a metabolic story: energy intake, energy expenditure, hormonal signalling, and how the body adapts under a calorie deficit. These guides cover what GLP-1 medications do to body composition, why protein and resistance training matter, and how to think about long-term metabolic health beyond the scale.
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Featured guides
Protein on a GLP-1: How Much, and Why It Matters So Much
When appetite drops, protein is the first thing to fall off the plate — and the one macro you can least afford to lose. Here's how to hit your target.
Nutrisense vs Signos vs Levels: Which CGM App?
Nutrisense vs Signos vs Levels compared: three app-based CGM programs for non-diabetics. Nutrisense for coaching, Signos for weight loss, Levels for analytics. Which fits you in 2026.
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Fatigue and Dehydration on a GLP-1: An Underrated Pair
Tiredness on a GLP-1 is often blamed on the drug itself — when the real culprits are under-eating and not drinking enough. Here's how to tell the difference.
Insulin Resistance Explained: Causes, Effects, and What to Do
Insulin resistance is one of the most common metabolic dysfunctions — and one of the least understood by people who have it. Here's what the science shows about causes, consequences, and interventions.
Is Slow Metabolism Real? What the Research Actually Shows
Most people attribute weight gain to a slow metabolism. The science is more nuanced — true metabolic rate differences between individuals are smaller than commonly believed, but they're real.
Is a CGM Worth It Without Diabetes?
An honest, even-handed answer to whether a continuous glucose monitor is worth it for a non-diabetic: who benefits, the real costs, and a clear verdict.
How to Use a CGM for Weight Loss
How to use a CGM for weight loss: a practical, step-by-step guide for non-diabetics. Learn your baseline, find your spikes, run A/B tests, and keep the lessons.
Sleep Deprivation and Weight Gain: The Hormone Link
One night of 4-hour sleep raises ghrelin 15–28%, drops leptin, and shifts food preference toward calorie-dense options. Multiply that over years.
Stress, Trauma, and Weight Gain: Why History Matters
Adverse Childhood Experiences correlate with adult obesity in a dose-dependent pattern across multiple cohorts. The biology underlying this is well-mapped — and it changes what compassionate treatment looks like.
Adaptive Thermogenesis: Why Metabolism Slows When You Diet
Lose 10% of your body weight and your resting metabolic rate falls by more than the smaller body would predict. That gap has a name — and three decades of research mapping how it works.
Is 'Metabolic Damage' Real? What the Research Says
Adaptive thermogenesis is documented and persistent. 'Permanent metabolic damage' is mostly myth. The distinction matters because it changes what someone with a long dieting history can reasonably expect.
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Other topic areas
01
The Science Behind GLP-1
Evidence-based explanations of GLP-1, semaglutide, appetite regulation, and modern obesity science.
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The Biology of Appetite and Hunger
Science-backed insights into hunger, satiety, cravings, and appetite hormones.
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What the Weight Loss Research Actually Shows
Breakdowns of modern obesity research, clinical studies, and emerging metabolic science.
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Modern GLP-1 Treatment Options
Educational content about modern weight management approaches and GLP-1-based therapies.
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