What the Weight Loss Research Actually Shows

Yo-Yo Dieting (Weight Cycling): Health Risks and How to Break the Cycle

Repeated cycles of loss and regain are independently associated with visceral fat redistribution, higher cardiovascular risk, and metabolic dysregulation — beyond the effects of obesity itself. The data make a quiet case for sustained treatment over repeated attempts.

Weight Regain After Stopping Ozempic: What the Research Actually Shows

STEP 4 randomised people who had already lost weight on semaglutide to either continue or switch to placebo. The placebo group regained two-thirds of their loss within a year — and the biology behind that pattern explains the rest.

Set Point Theory: Does Your Body Have a Defended Weight?

The phrase "set point" is technically imprecise — researchers prefer "defended range" — but the underlying observation is well-supported. Across fifty years of starvation studies, twin research, and modern hormonal trials, bodies push back when their weight is moved.

The All-or-Nothing Diet Trap: Why Restriction Always Leads to Overeating

Cognitive restraint theory predicts what dieters call "falling off the wagon" with mechanistic precision. The abstinence violation effect was named in 1985 — and explains why "starting over Monday" almost never works.

11 min read·Updated May 2026

Keto, Paleo, Intermittent Fasting — Why Popular Diets Don't Last

DIETFITS, A TO Z, PREDIMED. Long-term head-to-head diet trials reveal a stubborn pattern: at 12 months, the differences between approaches are smaller than the differences between adherent and non-adherent individuals.

11 min read·Updated May 2026

Why Low-Calorie Diets Backfire Long-Term

CALERIE trial data: 25% caloric restriction for two years. The participants lost weight. Then a quieter finding emerged about what their bodies did to compensate.

9 min read·Updated May 2026

Why Most People Regain Weight After a Diet — and Why It's Not Your Fault

Most people regain the weight they lose within five years. That statistic isn't evidence of weak willpower — it's evidence of powerful biology defending a weight your body considers its normal.

Why Diets Fail: The Biology Your Doctor Never Explained

Weight regain after dieting isn't a willpower failure — it's a predictable biological response involving hormones, metabolism, and brain chemistry. The science has been clear for decades.

9 min read·Updated May 2026

I've Tried Every Diet and Nothing Works: What Your Body Is Actually Doing

You've counted calories, cut carbs, tried fasting. The weight keeps coming back. This isn't a willpower problem — it's a predictable biological response that most doctors never explain.